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Vexing Microbes

Musings of an Infectious Disease Specialist

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Acute Kidney Injury with Concomitant Vancomycin & Pip/Tazo (Vancosyn, Vanczosyn, Vosyn)

29 April, 2017 by GAggreyMD Leave a Comment

Recently, a nephrologist I work with chased me down to ask my opinion of the new and interesting study that concludes concomitant vancomycin and piperacillin-tazobactam (hereforth to be called vancosyn) was more nephrotoxic than concomitant vancomycin and cefepime (vancopime). “Yes, indeed, I have heard the data but which study are you calling new?” I wondered. […]

Filed Under: Infectious Diseases Tagged With: Abx Resistance, Abx Stewardship, Antimicrobials, Checklist Medicine, Diagnostics, Save Abx, Sepsis, STI

Historic United Nations General Assembly Meeting on Antimicrobial Resistance

21 September, 2016 by GAggreyMD Leave a Comment

Today at the United Nations General Assembly Meeting, all 193 member countries are set to agree to combat antimicrobial resistance, “the biggest threat to modern medicine”. I couldn’t be happier. Antimicrobial resistance has been well-known to scientists since the first antibiotic, penicillin, was created. But it has only been in the last few years that […]

Filed Under: Infectious Diseases Tagged With: Abx Resistance, Antimicrobials, Save Abx

Risky Fluoroquinolones

19 August, 2016 by GAggreyMD Leave a Comment

The US Food and Drug Administration (FDA) issued a black box warning for the class of antibiotics known as fluoroquinolones which includes the popularly prescribed Levaquin (levofloxacin), Avelox (moxifloxacin), and Cipro (ciprofloxacin). The warning advises that the serious side effects associated with this class of antibiotics “generally outweigh the benefits for patients with acute sinusitis, […]

Filed Under: Infectious Diseases Tagged With: Abx Resistance, Abx Stewardship, Antimicrobials, Clinical Practice, Medical Education, Save Abx

Surviving Sepsis – A Word to the Wise…

12 July, 2012 by GAggreyMD 3 Comments

I just read a really awful heart-wrenching story in the New York Times today. It’s the story of Rory Staunton, a 12 year old boy in New York City who presented to his pediatrician’s office on a Thursday ill with fever, vomiting, and leg pain; was sent to the emergency room at NYU Langone where […]

Filed Under: Infectious Diseases Tagged With: Abx Stewardship, Healthcare, Medical Residency, Save Abx, Sepsis, Streptococcus, System Error

Bacteria are laughing at us!

30 September, 2011 by GAggreyMD Leave a Comment

I came across a nice article in the October issue of the Atlantic titled Resistance is Futile. It attempts to describe the problem of antibiotic resistance from an economic viewpoint. While I don’t understand all those nuances, despite my couple semesters of economics in college, I still think it’s an overall good read. I loved […]

Filed Under: Infectious Diseases Tagged With: Abx Resistance, In The News, Microbes, Save Abx

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